Peninsula Clinical Trials Unit: publications

Results and Protocol publications
Advanced Clinical practitioner
Doctor checks the health of the liver of the patient. Image courtesy of GettyImages

2024
THE ALD Study - Nature Reviews Gastroenterology & Hepatology – October 2024
An expert panel Consensus Statement on ALD without experts by experience
The personal impact is considerable for family caregivers at the end-of-life – BMJ Supportive & Palliative Care
25 Family caregiver socio-economic status, access to palliative care and patients’ place of death: a health survey for England study

2023
The potential for medicinal cannabis to help manage challenging behaviour in people with intellectual disability: A perspective review – Sage Journals – November 2023
Around 2% of the population have intellectual disabilities. Over one-third people with intellectual disabilities (PwID) present with ‘challenging behaviour’, which nosologically and diagnostically is an abstract concept.
The Myriad Study – Journal of the American Academy of Child & Adolescent Psychiatry – October 2023
Student- and School-Level Factors Associated With Mental Health and Well-Being in Early Adolescence
Treatment of age-related macular degeneration with aflibercept using a treat, extend and fixed protocol; A 4-year study of treatment outcomes, durability, safety and quality of life – Acta Ophthalmologica Journal – September 2023
The aim of this study was to provide outcomes, safety, durability and quality-of-life data with aflibercept using a modified treat, extend and fixed regime over 4 years.
A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile – Journal of Clinical and Experimental Neuropsychology – August 2023
The current study sought to test whether administering visuospatial and writing tests using a tablet (finger or stylus drawing), would demonstrate equivalence to traditional pencil and paper administration on ACEmobile.
The DIADS Study – International Journal of Environmental Research and Public Health – January 2023
Comparison of Diagnostic Profiles of Deaf and Hearing Children with a Diagnosis of Autism

2022
The e-coachER Study – International Journal of Behavioral Nutrition and Physical Activity – September 2022
A process evaluation, with mediation analysis, of a web-based intervention to augment primary care exercise referral schemes: the e-coachER randomised controlled trial
The PD Stat Study – Journal of Parkinson's Disease – July 2022
Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT

2021
Health risk behaviours among people with severe mental ill health during the COVID-19 pandemic – PLOS One – October 2021
Analysis of linked cohort data
The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation – Journal of Clinical Medicine – September 2021
Diagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptation
A mixed-method feasibility study of a novel transitional regime of incremental haemodialysis – Clinical and Experimental Nephrology – June 2021
Study design and protocol
The ADOS-2 Study – Journal of Autism and Developmental Disorders – March 2021
Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people
The EXPRESS Study – Annals of Clinical Biochemistry – February 2021
Evaluation of the MP Rapid 2019-NCOV IgM/IgG Combo POCT test vs an established platform-based method
The SARS-CoV-2 Study – Clinical Medicine Journal – January 2021
Review of hygiene adaptations among UK doctors in controlling the spread of SARS-CoV-2 infection

2020

2010 – 2019
The TACIT Study – Clinical Interventions in Aging – November 2019
Randomised Controlled Trial Of The Effect Of Tai Chi On Postural Balance Of People With Dementia
The Sorafenib Study – Journal of Neurology, Neurosurgery & Psychiatry – February 2019
Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2
The REACH-HF Trial – Chronic Illness – December 2015
Needs of caregivers in heart failure management: A qualitative study

This unit receives National Institute for Health and Care Research CTU Support Funding. This funding has been awarded to support the unit in developing and supporting NIHR trials.